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Title: Development of a field test kit for blue-green algal toxins 1994 (348/6/A) : R and D draft final report
Author: D. Baron
Document Type: Monograph
Annotation: EA additional title info: Biocode Ltd December 1994
Blue-green algal (cyanobacterial) toxins have been demonstrated as being biologically active in a number of species, but their toxicity in humans is undefined and warrants more thorough investigation. Microcvstin-LR is the major hepatotoxin produced by blue-green algae. It has a cyclic structure composed o f seven amino acids, with a molecular weight of approximately 1000Da. Other structural variants exist that differ by two amino acids. In R and D project 348 Biocode Limited was contracted by the National Rivers Authority to produce on-site testing kits using monoclonal antibodies. These kits would enable the easy, specific and rapid extraction and identification o f microcystin-LR and some structurally related analogues. This work required the development of novel monoclonal antibodies. Work commenced on the project in October 1991.
Publisher: National Rivers Authority
Publication Date: 1994
Publication Place: Bristol
Subject Keywords: Algal bloomsField experimentationIdentification
Taxonomic Keywords: Cyanobacteria
Extent: 14
Total file downloads: 266

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